Accession | PRJCA016745 | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Title | Single-cell profiling revealed tumor heterogeneity and microenvironment in surgically resectable esophageal squamous cell carcinoma with neoadjuvant chemoimmunotherapy | |||||||||||||||
Relevance | Medical | |||||||||||||||
Data types | Single cell sequencing | |||||||||||||||
Organisms | Homo sapiens | |||||||||||||||
Description | This study enrolled 22 patients diagnosed with stage II to IV ESCC, of whom 20 underwent neoadjuvant tislelizumab combined with chemotherapy before surgical removal and two were treated with camrelizumab plus chemotherapy before surgery. The dataset performed single-cell transcriptomic data of a total of 259,003 cells derived from 22 baseline and 24 post-NAT treatment samples of 22 stage II/III resectable ESCC patients. | |||||||||||||||
Sample scope | Multiisolate | |||||||||||||||
Release date | 2023-06-16 | |||||||||||||||
Publication |
|
|||||||||||||||
Grants |
|
|||||||||||||||
Submitter | Qiang Lu (luqiang@fmmu.edu.cn) | |||||||||||||||
Organization | Air Force Medical University | |||||||||||||||
Submission date | 2023-04-28 |
Resource name | Description |
---|---|
BioSample (46) show | - |