| 项目编号 |
PRJCA016919 |
| 项目标题 |
Multiomics Profiling Uncovers Pan-Cancer Immune Cell Dynamics in Immunotherapy Response |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
Raw sequence reads
Single cell sequencing
|
| 物种名称 |
Homo sapiens
microbial eukaryotic metagenome
|
| 描述信息 |
Immune checkpoint blockade (ICB) therapy has revolutionized cancer treatment, yet not all patients respond to the therapy. We employed a single-cell multiomics approach to unveil immune cell dynamics that underlie the response to ICB in pan-cancer samples at the pan-cancer level. Corresponding author: Xuexin Li (xuexin.li@ki.se) |
| 样品范围 |
Single cell |
| 发布日期 |
2024-06-03 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 39034339
|
A single-cell pan-cancer analysis to show the variability of tumor-infiltrating myeloid cells in immune checkpoint blockade
|
Nature Communications
|
10.1038/s41467-024-50478-8
|
2024
|
| 40054456
|
Deciphering immune predictors of immunotherapy response: A multiomics approach at the pan-cancer level
|
Cell Reports Medicine
|
10.1016/j.xcrm.2025.101992
|
2025
|
| 41187056
|
Protocol for decoding immune predictors of response to immunotherapy through pan-cancer multiomics analysis
|
STAR Protocols
|
10.1016/j.xpro.2025.104183
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
81860499
|
|
|
|
| 提交者 |
Lu
Pan (lu.pan@ki.se)
|
| 提交单位 |
Karolinska Institutet |
| 提交日期 |
2023-05-12 |
