| Accession |
PRJCA016919 |
| Title |
Multiomics Profiling Uncovers Pan-Cancer Immune Cell Dynamics in Immunotherapy Response |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
Raw sequence reads
Single cell sequencing
|
| Organisms |
Homo sapiens
microbial eukaryotic metagenome
|
| Description |
Immune checkpoint blockade (ICB) therapy has revolutionized cancer treatment, yet not all patients respond to the therapy. We employed a single-cell multiomics approach to unveil immune cell dynamics that underlie the response to ICB in pan-cancer samples at the pan-cancer level. Corresponding author: Xuexin Li (xuexin.li@ki.se) |
| Sample scope |
Single cell |
| Release date |
2024-06-03 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 39034339
|
A single-cell pan-cancer analysis to show the variability of tumor-infiltrating myeloid cells in immune checkpoint blockade
|
Nature Communications
|
10.1038/s41467-024-50478-8
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
81860499
|
|
|
|
| Submitter |
Lu
Pan (lu.pan@ki.se)
|
| Organization |
Karolinska Institutet |
| Submission date |
2023-05-12 |
