Accession PRJCA017149
Title Three near-complete genome assemblies reveal substantial centromere dynamics from diploid to tetraploid in Brachypodium genus
Relevance Evolution
Data types Genome sequencing and assembly
Organisms Brachypodium
Description Centromeres are critical for maintaining genomic stability in eukaryotes, and their turnover can shape genome architectures and drive karyotype evolution. However, the co-evolution of centromeres from different species in allopolyploids over millions of years remains largely unknown. Here, we constructed three near-complete genome assemblies for B. hybridum, B. distachyon, and B. stacei, and provided the first comprehensive comparison of previously inaccessible centromeric regions across species with different polyploidy levels. Our findings offer novel scientific insights into the sequences, structural, and epigenetic variations in centromeres of closely related species, and their potential roles during polyploidy adaptions at base-pair resolution.
Sample scope Multispecies
Release date 2024-02-09
Grants
Agency program Grant ID Grant title
National Key Research and Development Program of China 2021YFF1000800
National Natural Science Foundation of China (NSFC) 32170571
Fundamental Research Funds for the Central Universities 2021ZKPY008
Hainan Yazhou Bay Seed Laboratory B21HJ0504
Natural Science Foundation of Hubei Province of China 2021CFB097
Submitter Handong Su (shandong@mail.hzau.edu.cn)
Organization National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University
Submission date 2023-05-10

Project Data

Resource name Description
BioSample (5) -
SAMC1255401 IBd483_Hi-C
SAMC1255400 Bst99_Hi-C
SAMC1255399 IBd483_HiFi
SAMC1255398 Bst99_HiFi
SAMC1255397 Bdi21_HiFi
GSA (1) -
CRA011125 Three near-complete genome assemblies reveal substantial centromere dynamics from diploid to tetraploid in Brachypodium genus