| 项目编号 |
PRJCA017804 |
| 项目标题 |
Molecular subtypes of neuroendocrine carcinomas |
| 涉及领域 |
Medical |
| 数据类型 |
Epigenomics
Transcriptome or Gene expression
Raw sequence reads
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Neuroendocrine carcinomas (NECs) are extremely lethal malignancies that can arise at almost any anatomic site. They are characterized by rapid growth, early metastasis, and significant heterogeneity. To identify determinants of their heterogeneity, we conducted transcriptomic sequencing, transposase-accessible chromatin sequencing, and spatial transcriptomic sequencing on NECs. We revealed the key role of master transcriptional factors in determining the molecular subtypes of NECs. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2024-04-20 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 38788718
|
Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators
|
Cancer Cell
|
10.1016/j.ccell.2024.05.002
|
2024
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Beijing Municipal Science & Technology
|
|
Z221100007422011
|
|
| Beijing Municipal Science & Technology
|
|
Z191100001119049
|
|
| Chinese Academy of Medical Sciences
|
|
2021-I2M-1-050
|
|
| Chinese Academy of Medical Sciences
|
|
2021-I2M-1-012
|
|
| China Association for Science and Technology
|
|
2019QNRC001
|
|
|
|
| 提交者 |
Nan
Sun (sunnan@cicams.ac.cn)
|
| 提交单位 |
Cancer Hospital, Chinese Academy of Medical Sciences |
| 提交日期 |
2023-06-20 |
