| Accession |
PRJCA017920 |
| Title |
Glucose promoting the early embryonic development by increasing the lipid synthesis at 2-cell stage |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Mus musculus
|
| Description |
The optimization of culture conditions is one of the main strategies to improve the embryo develeopment competence in in vitro fertilization (IVF). Glucose is an important carbon source while also exists in the oviductal fluid in vivo, the effect of glucose in embryo development microenvironment is still unclear. Our data indicated the glucose may promote the development competence through increasing the lipid biosynthesis to overcoming the 2-Cell block. These findings were helpful for the further optimization of IVF culture media, as well as the estimation of embryo quality using metabolites in the culture media. |
| Sample scope |
Multiisolate |
| Release date |
2023-06-26 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 37534102
|
Glucose promoting the early embryonic development by increasing the lipid synthesis at 2-cell stage
|
Frontiers in Cell and Developmental Biology
|
10.3389/fcell.2023.1208501
|
2023
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
82271644
|
|
|
|
| Submitter |
Zhigang
Xue (xuezg@tongji.edu.cn)
|
| Organization |
Tongji University |
| Submission date |
2023-06-26 |
