| 项目编号 |
PRJCA017920 |
| 项目标题 |
Glucose promoting the early embryonic development by increasing the lipid synthesis at 2-cell stage |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
The optimization of culture conditions is one of the main strategies to improve the embryo develeopment competence in in vitro fertilization (IVF). Glucose is an important carbon source while also exists in the oviductal fluid in vivo, the effect of glucose in embryo development microenvironment is still unclear. Our data indicated the glucose may promote the development competence through increasing the lipid biosynthesis to overcoming the 2-Cell block. These findings were helpful for the further optimization of IVF culture media, as well as the estimation of embryo quality using metabolites in the culture media. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2023-06-26 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 37534102
|
Glucose promoting the early embryonic development by increasing the lipid synthesis at 2-cell stage
|
Frontiers in Cell and Developmental Biology
|
10.3389/fcell.2023.1208501
|
2023
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
82271644
|
|
|
|
| 提交者 |
Zhigang
Xue (xuezg@tongji.edu.cn)
|
| 提交单位 |
Tongji University |
| 提交日期 |
2023-06-26 |
