Accession PRJCA017924
Title TF-BTseq usage
Relevance Medical
Data types Targeted Locus (Loci)
Transcriptome or Gene expression
Organisms Homo sapiens
Description Here, we have developed a targeted full-length BCR/TCR transcript sequencing workflow (TF-BTseq) with high accuracy and quantitative ability based on nanopore sequencing platforms. Then, TF-BTseq was applied to characterize BCR/TCR repertoires of peripheral blood from patients with acute lymphocytic leukemia (ALL) and patients with allergic diseases (AD), tumor-infiltrating lymphocytes (TILs) in prostate cancer tissues, and lymphocytes in psoriasis tissues.
Sample scope Multiisolate
Release date 2024-08-24
Publication
PubMed ID Article title Journal name DOI Year
39288005 Full-Length Immune Repertoire Reconstruction and Profiling at the Transcriptome Level Using Long-Read Sequencing Clinical Chemistry 10.1093/clinchem/hvae138 2024
Grants
Agency program Grant ID Grant title
No funding support
Submitter Fei Xiao (xiaofei3965@bjhmoh.cn)
Organization Beijing Hospital
Submission date 2023-06-27

Project Data

Resource name Description