| 项目编号 |
PRJCA017996 |
| 项目标题 |
Effects of gestational diabetes on DNA methylome of oocytes |
| 涉及领域 |
Medical |
| 数据类型 |
Epigenomics
Transcriptome or Gene expression
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
Gestational diabetes (GDM) is a common gestational disease and has negative effects on offspring at a long term. But the mechanisms are not well known. In this project, we investigate the effects of GDM on DNA methylation of offspring oocytes and its inheritance. |
| 样品范围 |
Single cell |
| 发布日期 |
2024-11-04 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 39747080
|
Gestational diabetes mellitus causes genome hyper-methylation of oocyte via increased EZH2
|
Nature Communications
|
10.1038/s41467-024-55499-x
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
31872312
|
|
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2022YFC2703501
|
|
|
|
| 提交者 |
Zhao-Jia
Ge (zjge@qau.edu.cn)
|
| 提交单位 |
Qingdao Agricultural University |
| 提交日期 |
2023-06-29 |
