Accession |
PRJCA018014 |
Title |
Inheritance and mechanism of disturbed DNA methylation in oocytes induced by maternal obesity |
Relevance |
Medical |
Data types |
Epigenomics
|
Organisms |
Mus musculus
Mus
|
Description |
Maternal obesity has adverse effects on offspring health, but the underlying mechanisms are not well elucidated. In this project, we find the disturbed DNA methylation in oocytes induced by obesity can inherited by F2, and increased DNMTs are involved in the hyper-methylation of oocytes. |
Sample scope |
Single cell |
Release date |
2024-11-12 |
Grants |
Agency |
program |
Grant ID |
Grant title |
National Natural Science Foundation of China (NSFC)
|
General Program
|
31872312
|
|
|
Submitter |
Zhao-Jia
Ge (zjge@qau.edu.cn)
|
Organization |
Qingdao Agricultural University |
Submission date |
2023-06-30 |