Accession PRJCA018150
Title Protein profiles of individual extracellular vesicle surfaces in a variety of body fluids from APP/PS1 transgenic mice and AD patients
Relevance Medical
Data types Single cell sequencing
Organisms mixed sample
Description Diagnosis of Alzheimers disease (AD) in a non-invasive and effortless manner remains challenging. We detected profiles of extracellular vesicle (EV) surface proteins at single EV level in a variety of body fluids from APP/PS1 transgenic mice and AD patients, including irrigation solution, urine and blood, using proximity-barcoding assay (PBA).
Sample scope Multispecies
Release date 2024-04-23
Publication
PubMed ID Article title Journal name DOI Year
38602321 Surface protein profiling and subtyping of extracellular vesicles in body fluids reveals non-CSF biomarkers of Alzheimer's disease Journal of Extracellular Vesicles 10.1002/jev2.12432 2024
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) General Program 81971300
National Natural Science Foundation of China (NSFC) General Program 82101429
National Natural Science Foundation of China (NSFC) General Program 82171776
Science and Technology Innovation Commission of Shenzhen General Program JCYJ20180228162815750
Science and Technology Innovation Commission of Shenzhen General Program JCYJ20190806164203496
Science and Technology Innovation Commission of Shenzhen General Program JCYJ20210324103213037
Submitter You Cai (caiyou626@outlook.com)
Organization Shenzhen University
Submission date 2023-03-06

Project Data

Resource name Description