Accession |
PRJCA018150 |
Title |
Protein profiles of individual extracellular vesicle surfaces in a variety of body fluids from APP/PS1 transgenic mice and AD patients |
Relevance |
Medical |
Data types |
Single cell sequencing
|
Organisms |
mixed sample
|
Description |
Diagnosis of Alzheimers disease (AD) in a non-invasive and effortless manner remains challenging. We detected profiles of extracellular vesicle (EV) surface proteins at single EV level in a variety of body fluids from APP/PS1 transgenic mice and AD patients, including irrigation solution, urine and blood, using proximity-barcoding assay (PBA). |
Sample scope |
Multispecies |
Release date |
2024-04-23 |
Publication |
PubMed ID |
Article title |
Journal name |
DOI |
Year |
38602321
|
Surface protein profiling and subtyping of extracellular vesicles in body fluids reveals non-CSF biomarkers of Alzheimer's disease
|
Journal of Extracellular Vesicles
|
10.1002/jev2.12432
|
2024
|
|
Grants |
Agency |
program |
Grant ID |
Grant title |
National Natural Science Foundation of China (NSFC)
|
General Program
|
81971300
|
|
National Natural Science Foundation of China (NSFC)
|
General Program
|
82101429
|
|
National Natural Science Foundation of China (NSFC)
|
General Program
|
82171776
|
|
Science and Technology Innovation Commission of Shenzhen
|
General Program
|
JCYJ20180228162815750
|
|
Science and Technology Innovation Commission of Shenzhen
|
General Program
|
JCYJ20190806164203496
|
|
Science and Technology Innovation Commission of Shenzhen
|
General Program
|
JCYJ20210324103213037
|
|
|
Submitter |
You
Cai (caiyou626@outlook.com)
|
Organization |
Shenzhen University |
Submission date |
2023-03-06 |