| Accession |
PRJCA018203 |
| Title |
Urinary tumor DNA MRD analysis to identify responders to neoadjuvant immunotherapy in muscle-invasive bladder cancer |
| Relevance |
Medical |
| Data types |
Exome
Targeted Locus (Loci)
|
| Organisms |
Homo sapiens
|
| Description |
Bladder preservation is a viable option for some muscle-invasive bladder cancer (MIBC) patients, but an effective noninvasive biomarker test to accurately identify promising candidates is lacking. Here we present the clinical application of a novel tissue-agnostic, urine-based minimal residual disease (MRD) assay in the neoadjuvant setting for personalized disease surveillance and actionable target identification to facilitate bladder-sparing treatment approaches. |
| Sample scope |
Multiisolate |
| Release date |
2023-07-27 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
82172596
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82173076
|
|
| National Natural Science Foundation of China (NSFC)
|
|
81902562
|
|
|
|
| Submitter |
Haige
Chen (rjbladder@163.com)
|
| Organization |
Renji Hospital, School of Medicine, Shanghai Jiao Tong University |
| Submission date |
2023-07-07 |
