| Accession |
PRJCA018299 |
| Title |
Modeling the precise interaction of glioblastoma with human brain region-specific organoids |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Homo sapiens
|
| Description |
To investigate the interactions between glioblastoma and different types of neurons, we used human ESCs to generate dorsal and ventral forebrain organoids (DO/VO), which were subsequently co-cultured with glioblastoma organoids (GB) in three different ways. After a two-week co-culture period, we performed RNA sequencing on a total of 108 organoids, including groups that were co-cultured in different ways and controls that were not co-cultured. |
| Sample scope |
Monoisolate |
| Release date |
2024-01-27 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 38390494
|
Modeling the precise interaction of glioblastoma with human brain region-specific organoids
|
iScience
|
10.1016/j.isci.2024.109111
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
32070956
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
82073166
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
82273203
|
|
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Research and Development Program of China
|
2021ZD0202500
|
|
| National Key Research and Development Program of China
|
General Program
|
2020YFA0804200
|
|
| Natural Science Foundation of Shanghai
|
General Program
|
20ZR1405200
|
|
|
|
| Submitter |
Zhicheng
Shao (zcshao@fudan.edu.cn)
|
| Organization |
Institute For Translational Brain Research, Fudan University |
| Submission date |
2023-07-12 |
