| Accession |
PRJCA018527 |
| Title |
Unraveling the Influence of the Cervical Cancer Tumor Immune Microenvironment on Treatment Response and Prognosis: Insights from Single-Cell Transcriptome Sequencing |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
Raw sequence reads
Single cell sequencing
|
| Organisms |
Homo sapiens
|
| Description |
Single-cell transcriptome sequencing was conducted on primary tumors or metastatic lesions from patients diagnosed with cervical cancer, who were undergoing different treatment modalities. The primary objective of this investigation was to explore the biological attributes of the tumors and the composition of the immune microenvironment that could potentially impact treatment effectiveness and prognosis. Ultimately, the study aimed to provide valuable bioinformatic insights to identify a specific subgroup of patients who might derive greater benefits from the treatment. |
| Sample scope |
Single cell |
| Release date |
2023-08-10 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 38199610
|
Multiomics profiling reveals the benefits of gamma-delta (γδ) T lymphocytes for improving the tumor microenvironment, immunotherapy efficacy and prognosis in cervical cancer
|
Journal for Immunotherapy of Cancer
|
10.1136/jitc-2023-008355
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Tianjin Medical University Cancer Institute and Hospital
|
Hospital-level research project
|
LX202210016
|
|
|
|
| Submitter |
Zhiyong
Yuan (zyuan@tmu.edu.cn)
|
| Organization |
Tianjin Medical University Cancer Institute & Hospital |
| Submission date |
2023-07-21 |
