Accession

PRJCA018532

Title

Multi-omics reveal host-microbiota interactions in primary biliary cholangitis

Relevance

Medical

Data types

Metagenome
Raw sequence reads

Organisms

Homo sapiens environmental sample
human gut metagenome

Description

To dissect the gut microbiome dysbiosis in PBC, we performed stool metagenome, metabolome, and serum metabolome profiling and collected detailed metadata from a cohort of 132 UDCA naive-patients with PBC and 131 healthy controls matched for geography, age, sex, and BMI.

Sample scope

Environment

Release date

2023-07-22

Publication

PubMed ID	Article title	Journal name	DOI	Year
	Gut microbiome pattern impacts treatment response in primary biliary cholangitis	Med	10.1016/j.medj.2024.08.003	2024

Grants

Agency	program	Grant ID	Grant title
National Natural Science Foundation of China (NSFC)		81922010
National Natural Science Foundation of China (NSFC)		82130017
National Natural Science Foundation of China (NSFC)		82070583
National Natural Science Foundation of China (NSFC)		82000532
National Natural Science Foundation of China (NSFC)		82200595
Shanghai Municipal Science and Technology Committee		20XD1422500
Shanghai Education Development Foundation and Shanghai Municipal Education Commission		18SG17

Submitter

Xiong Ma (maxiongmd@hotmail.com)

Organization

Renji Hospital, School of Medicine, Shanghai Jiao Tong University

Submission date

2023-07-22

Project Data

Resource name	Description
BioSample (263) show	-
SAMC2954283	fecal metagenomics sequencing
SAMC2954282	fecal metagenomics sequencing
SAMC2954281	fecal metagenomics sequencing
SAMC2954280	fecal metagenomics sequencing
SAMC2954279	fecal metagenomics sequencing
SAMC2954278	fecal metagenomics sequencing
SAMC2954277	fecal metagenomics sequencing
SAMC2954276	fecal metagenomics sequencing
SAMC2954275	fecal metagenomics sequencing
SAMC2954274	fecal metagenomics sequencing
SAMC2954273	fecal metagenomics sequencing
SAMC2954272	fecal metagenomics sequencing
SAMC2954271	fecal metagenomics sequencing
SAMC2954270	fecal metagenomics sequencing
SAMC2954269	fecal metagenomics sequencing
SAMC2954268	fecal metagenomics sequencing
SAMC2954267	fecal metagenomics sequencing
SAMC2954266	fecal metagenomics sequencing
SAMC2954265	fecal metagenomics sequencing
SAMC2954264	fecal metagenomics sequencing
SAMC2954263	fecal metagenomics sequencing
SAMC2954262	fecal metagenomics sequencing
SAMC2954261	fecal metagenomics sequencing
SAMC2954260	fecal metagenomics sequencing
SAMC2954259	fecal metagenomics sequencing
SAMC2954258	fecal metagenomics sequencing
SAMC2954257	fecal metagenomics sequencing
SAMC2954256	fecal metagenomics sequencing
SAMC2954255	fecal metagenomics sequencing
SAMC2954254	fecal metagenomics sequencing
SAMC2954253	fecal metagenomics sequencing
SAMC2954252	fecal metagenomics sequencing
SAMC2954251	fecal metagenomics sequencing
SAMC2954250	fecal metagenomics sequencing
SAMC2954249	fecal metagenomics sequencing
SAMC2954248	fecal metagenomics sequencing
SAMC2954247	fecal metagenomics sequencing
SAMC2954246	fecal metagenomics sequencing
SAMC2954245	fecal metagenomics sequencing
SAMC2954244	fecal metagenomics sequencing
SAMC2954243	fecal metagenomics sequencing
SAMC2954242	fecal metagenomics sequencing
SAMC2954241	fecal metagenomics sequencing
SAMC2954240	fecal metagenomics sequencing
SAMC2954239	fecal metagenomics sequencing
SAMC2954238	fecal metagenomics sequencing
SAMC2954237	fecal metagenomics sequencing
SAMC2954236	fecal metagenomics sequencing
SAMC2954235	fecal metagenomics sequencing
SAMC2954234	fecal metagenomics sequencing
SAMC2954233	fecal metagenomics sequencing
SAMC2954232	fecal metagenomics sequencing
SAMC2954231	fecal metagenomics sequencing
SAMC2954230	fecal metagenomics sequencing
SAMC2954229	fecal metagenomics sequencing
SAMC2954228	fecal metagenomics sequencing
SAMC2954227	fecal metagenomics sequencing
SAMC2954226	fecal metagenomics sequencing
SAMC2954225	fecal metagenomics sequencing
SAMC2954224	fecal metagenomics sequencing
SAMC2954223	fecal metagenomics sequencing
SAMC2954222	fecal metagenomics sequencing
SAMC2954221	fecal metagenomics sequencing
SAMC2954220	fecal metagenomics sequencing
SAMC2954219	fecal metagenomics sequencing
SAMC2954218	fecal metagenomics sequencing
SAMC2954217	fecal metagenomics sequencing
SAMC2954216	fecal metagenomics sequencing
SAMC2954215	fecal metagenomics sequencing
SAMC2954214	fecal metagenomics sequencing
SAMC2954213	fecal metagenomics sequencing
SAMC2954212	fecal metagenomics sequencing
SAMC2954211	fecal metagenomics sequencing
SAMC2954210	fecal metagenomics sequencing
SAMC2954209	fecal metagenomics sequencing
SAMC2954208	fecal metagenomics sequencing
SAMC2954207	fecal metagenomics sequencing
SAMC2954206	fecal metagenomics sequencing
SAMC2954205	fecal metagenomics sequencing
SAMC2954204	fecal metagenomics sequencing
SAMC2954203	fecal metagenomics sequencing
SAMC2954202	fecal metagenomics sequencing
SAMC2954201	fecal metagenomics sequencing
SAMC2954200	fecal metagenomics sequencing
SAMC2954199	fecal metagenomics sequencing
SAMC2954198	fecal metagenomics sequencing
SAMC2954197	fecal metagenomics sequencing
SAMC2954196	fecal metagenomics sequencing
SAMC2954195	fecal metagenomics sequencing
SAMC2954194	fecal metagenomics sequencing
SAMC2954193	fecal metagenomics sequencing
SAMC2954192	fecal metagenomics sequencing
SAMC2954191	fecal metagenomics sequencing
SAMC2954190	fecal metagenomics sequencing
SAMC2954189	fecal metagenomics sequencing
SAMC2954188	fecal metagenomics sequencing
SAMC2954187	fecal metagenomics sequencing
SAMC2954186	fecal metagenomics sequencing
SAMC2954185	fecal metagenomics sequencing
SAMC2954184	fecal metagenomics sequencing
SAMC2954183	fecal metagenomics sequencing
SAMC2954182	fecal metagenomics sequencing
SAMC2954181	fecal metagenomics sequencing
SAMC2954180	fecal metagenomics sequencing
SAMC2954179	fecal metagenomics sequencing
SAMC2954178	fecal metagenomics sequencing
SAMC2954177	fecal metagenomics sequencing
SAMC2954176	fecal metagenomics sequencing
SAMC2954175	fecal metagenomics sequencing
SAMC2954174	fecal metagenomics sequencing
SAMC2954173	fecal metagenomics sequencing
SAMC2954172	fecal metagenomics sequencing
SAMC2954171	fecal metagenomics sequencing
SAMC2954170	fecal metagenomics sequencing
SAMC2954169	fecal metagenomics sequencing
SAMC2954168	fecal metagenomics sequencing
SAMC2954167	fecal metagenomics sequencing
SAMC2954166	fecal metagenomics sequencing
SAMC2954165	fecal metagenomics sequencing
SAMC2954164	fecal metagenomics sequencing
SAMC2954163	fecal metagenomics sequencing
SAMC2954162	fecal metagenomics sequencing
SAMC2954161	fecal metagenomics sequencing
SAMC2954160	fecal metagenomics sequencing
SAMC2954159	fecal metagenomics sequencing
SAMC2954158	fecal metagenomics sequencing
SAMC2954157	fecal metagenomics sequencing
SAMC2954156	fecal metagenomics sequencing
SAMC2954155	fecal metagenomics sequencing
SAMC2954154	fecal metagenomics sequencing
SAMC2954153	fecal metagenomics sequencing
SAMC2954152	fecal metagenomics sequencing
SAMC2954151	fecal metagenomics sequencing
SAMC2954150	fecal metagenomics sequencing
SAMC2954149	fecal metagenomics sequencing
SAMC2954148	fecal metagenomics sequencing
SAMC2954147	fecal metagenomics sequencing
SAMC2954146	fecal metagenomics sequencing
SAMC2954145	fecal metagenomics sequencing
SAMC2954144	fecal metagenomics sequencing
SAMC2954143	fecal metagenomics sequencing
SAMC2954142	fecal metagenomics sequencing
SAMC2954141	fecal metagenomics sequencing
SAMC2954140	fecal metagenomics sequencing
SAMC2954139	fecal metagenomics sequencing
SAMC2954138	fecal metagenomics sequencing
SAMC2954137	fecal metagenomics sequencing
SAMC2954136	fecal metagenomics sequencing
SAMC2954135	fecal metagenomics sequencing
SAMC2954134	fecal metagenomics sequencing
SAMC2954133	fecal metagenomics sequencing
SAMC2954132	fecal metagenomics sequencing
SAMC2954131	fecal metagenomics sequencing
SAMC2954130	fecal metagenomics sequencing
SAMC2954129	fecal metagenomics sequencing
SAMC2954128	fecal metagenomics sequencing
SAMC2954127	fecal metagenomics sequencing
SAMC2954126	fecal metagenomics sequencing
SAMC2954125	fecal metagenomics sequencing
SAMC2954124	fecal metagenomics sequencing
SAMC2954123	fecal metagenomics sequencing
SAMC2954122	fecal metagenomics sequencing
SAMC2954121	fecal metagenomics sequencing
SAMC2954120	fecal metagenomics sequencing
SAMC2954119	fecal metagenomics sequencing
SAMC2954118	fecal metagenomics sequencing
SAMC2954117	fecal metagenomics sequencing
SAMC2954116	fecal metagenomics sequencing
SAMC2954115	fecal metagenomics sequencing
SAMC2954114	fecal metagenomics sequencing
SAMC2954113	fecal metagenomics sequencing
SAMC2954112	fecal metagenomics sequencing
SAMC2954111	fecal metagenomics sequencing
SAMC2954110	fecal metagenomics sequencing
SAMC2954109	fecal metagenomics sequencing
SAMC2954108	fecal metagenomics sequencing
SAMC2954107	fecal metagenomics sequencing
SAMC2954106	fecal metagenomics sequencing
SAMC2954105	fecal metagenomics sequencing
SAMC2954104	fecal metagenomics sequencing
SAMC2954103	fecal metagenomics sequencing
SAMC2954102	fecal metagenomics sequencing
SAMC2954101	fecal metagenomics sequencing
SAMC2954100	fecal metagenomics sequencing
SAMC2954099	fecal metagenomics sequencing
SAMC2954098	fecal metagenomics sequencing
SAMC2954097	fecal metagenomics sequencing
SAMC2954096	fecal metagenomics sequencing
SAMC2954095	fecal metagenomics sequencing
SAMC2954094	fecal metagenomics sequencing
SAMC2954093	fecal metagenomics sequencing
SAMC2954092	fecal metagenomics sequencing
SAMC2954091	fecal metagenomics sequencing
SAMC2954090	fecal metagenomics sequencing
SAMC2954089	fecal metagenomics sequencing
SAMC2954088	fecal metagenomics sequencing
SAMC2954087	fecal metagenomics sequencing
SAMC2954086	fecal metagenomics sequencing
SAMC2954085	fecal metagenomics sequencing
SAMC2954084	fecal metagenomics sequencing
SAMC2954083	fecal metagenomics sequencing
SAMC2954082	fecal metagenomics sequencing
SAMC2954081	fecal metagenomics sequencing
SAMC2954080	fecal metagenomics sequencing
SAMC2954079	fecal metagenomics sequencing
SAMC2954078	fecal metagenomics sequencing
SAMC2954077	fecal metagenomics sequencing
SAMC2954076	fecal metagenomics sequencing
SAMC2954075	fecal metagenomics sequencing
SAMC2954074	fecal metagenomics sequencing
SAMC2954073	fecal metagenomics sequencing
SAMC2954072	fecal metagenomics sequencing
SAMC2954071	fecal metagenomics sequencing
SAMC2954070	fecal metagenomics sequencing
SAMC2954069	fecal metagenomics sequencing
SAMC2954068	fecal metagenomics sequencing
SAMC2954067	fecal metagenomics sequencing
SAMC2954066	fecal metagenomics sequencing
SAMC2954065	fecal metagenomics sequencing
SAMC2954064	fecal metagenomics sequencing
SAMC2954063	fecal metagenomics sequencing
SAMC2954062	fecal metagenomics sequencing
SAMC2954061	fecal metagenomics sequencing
SAMC2954060	fecal metagenomics sequencing
SAMC2954059	fecal metagenomics sequencing
SAMC2954058	fecal metagenomics sequencing
SAMC2954057	fecal metagenomics sequencing
SAMC2954056	fecal metagenomics sequencing
SAMC2954055	fecal metagenomics sequencing
SAMC2954054	fecal metagenomics sequencing
SAMC2954053	fecal metagenomics sequencing
SAMC2954052	fecal metagenomics sequencing
SAMC2954051	fecal metagenomics sequencing
SAMC2954050	fecal metagenomics sequencing
SAMC2954049	fecal metagenomics sequencing
SAMC2954048	fecal metagenomics sequencing
SAMC2954047	fecal metagenomics sequencing
SAMC2954046	fecal metagenomics sequencing
SAMC2954045	fecal metagenomics sequencing
SAMC2954044	fecal metagenomics sequencing
SAMC2954043	fecal metagenomics sequencing
SAMC2954042	fecal metagenomics sequencing
SAMC2954041	fecal metagenomics sequencing
SAMC2954040	fecal metagenomics sequencing
SAMC2954039	fecal metagenomics sequencing
SAMC2954038	fecal metagenomics sequencing
SAMC2954037	fecal metagenomics sequencing
SAMC2954036	fecal metagenomics sequencing
SAMC2954035	fecal metagenomics sequencing
SAMC2954034	fecal metagenomics sequencing
SAMC2954033	fecal metagenomics sequencing
SAMC2954032	fecal metagenomics sequencing
SAMC2954031	fecal metagenomics sequencing
SAMC2954030	fecal metagenomics sequencing
SAMC2954029	fecal metagenomics sequencing
SAMC2954028	fecal metagenomics sequencing
SAMC2954027	fecal metagenomics sequencing
SAMC2954026	fecal metagenomics sequencing
SAMC2954025	fecal metagenomics sequencing
SAMC2954024	fecal metagenomics sequencing
SAMC2954023	fecal metagenomics sequencing
SAMC2954022	fecal metagenomics sequencing
SAMC2954021	fecal metagenomics sequencing