Accession |
PRJCA018599 |
Title |
Study on the application value of whole-genome sequencing in the evolution, transmission and treatment outcome of drug-resistant Mycobacterium tuberculosis strains |
Relevance |
Medical |
Data types |
Whole genome sequencing
Raw sequence reads
|
Organisms |
Mycobacterium tuberculosis
|
Description |
In recent years, based on genomic DNA, the whole-genome sequencing technology (WGS) integrated with computer technology has provided a comprehensive description of the genomic characteristics of drug-resistant strains of Mycobacterium tuberculosis. This has filled the research gaps in the evolution and transmission of drug-resistant tuberculosis, as well as the mechanisms of resistance to traditional and new anti-tuberculosis drugs. It has laid a solid technological foundation for the comprehensive, accurate, and integrated determination of the evolution, transmission and drug resistance of Mycobacterium tuberculosis. Therefore, the application of WGS technology in the local area for the study of drug-resistant pulmonary tuberculosis transmission and treatment holds significant clinical and public health importance. |
Sample scope |
Multiisolate |
Release date |
2023-10-27 |
Grants |
Agency |
program |
Grant ID |
Grant title |
Department of Science and Technology of Zhejiang Province
|
Zhejiang Provincial Basic Public Welfare Research Program Project of China
|
LTGY23H190001
|
|
Department of Science and Technology of Zhejiang Province
|
Zhejiang Provincial Basic Public Welfare Research Program Project of China
|
LTGY23H190002
|
|
|
Submitter |
Yang
Che (13805876046@163.com)
|
Organization |
Ningbo Municipal Center for Disease Control and Prevention |
Submission date |
2023-07-26 |