| 项目编号 | PRJCA018627 | ||||||||||
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| 项目标题 | wheat gene transcriptional network | ||||||||||
| 涉及领域 | Agricultural | ||||||||||
| 数据类型 |
Epigenomics
Map Phenotype or Genotype Transcriptome or Gene expression Variation Raw sequence reads |
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| 物种名称 | Triticum aestivum | ||||||||||
| 描述信息 | Bread wheat (Triticum aestivum L.) is one of the most important cereal crops and spike architecture influences both grain weight and grain number per spike, which would determine the grain yield. However, the complex wheat genome, narrow genetic diversity and the influence of various environmental factors pose challenges in mapping the casual mutation for the variation of panicle traits. Here, we systematically identify genes involved in spike formation by integrating the genomic variation based genetic analysis and gene regulatory network (GRN) controlling young spike development in wheat. We obtained 169 loci that are responsible for variation of spike trait through GWAS and metaQTL analysis. GRN for young inflorescence at spikelet meristem (SM) and floret meristem (FM) stages, largely responding for number of spikelet and grains per spikelet respectively were constructed by integrating transcriptome, epigenome, eQTL, and protein-protein interactome and 321 genes were identified to be key regulators for young spike development. By integrating information from genetic variation and regulatory networks, we identified 310 candidate genes that influence the performance of spike trait in wheat and the functions of ZF, VRT2-B and SPL15-A was verified. | ||||||||||
| 样品范围 | Monoisolate | ||||||||||
| 发布日期 | 2024-03-02 | ||||||||||
| 出版信息 |
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| 项目资金来源 |
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| 提交者 | CHAO HE (hechao7021@163.com) | ||||||||||
| 提交单位 | Huazhong agricultural university | ||||||||||
| 提交日期 | 2023-07-27 |