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Accession PRJCA018683
Title Single-cell transcriptomic landscape deciphers novel olfactory neuroblastoma subtypes and intra-tumoral heterogeneity
Relevance Medical
Data types Single cell sequencing
Organisms Homo sapiens
Description Object: To explore the intra- and inter-tumoral heterogeneity of olfactory neuroblastoma (ONB). To discover ONB subtypes with distinctive expression features and different putative cellular origins, implying potential treatment strategies. To depict the tumor microenvironment landscape and cellular crosstalk with tumor cells. Methods: 10X genomics Single-cell RNA sequencing of 10 treatment-naive ONBs was conducted.
Sample scope Multiisolate
Release date 2024-04-25
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China 81970856
National Key Clinical Specialty Construction Project Z155080000004
Shanghai Science and Technology Committee Foundation 21JC1401100
Shanghai Xuhui District Science and Technology Committee Foundation No.2021-008
Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences (CIFMS) 2019-I2M-5-003 The New Technologies of Endoscopic Surgery in Skull Base Tumor
Shanghai Municipal Key Clinical Specialty shslczdzk00801
Shanghai Shen Kang Hospital Development Center SHDC22021214
Science and Technology Commission of Shanghai Municipality 20Y11902000
Science and Technology Commission of Shanghai Municipality 21ZR1411700
Submitter Hongmeng Yu (hongmengyush@163.com)
Organization Eye & ENT Hospital of Fudan University
Submission date 2023-07-28

Project Data

Resource name Description
BioSample (10)  show -