| 项目编号 |
PRJCA018716 |
| 项目标题 |
Biomarkers of Response to Immunotherapy in dMMR/MSI-H Colorectal Cancer |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
Variation
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
In this study, we analyzed multi-omics data of dMMR/MSI-H CRC in patients treated with neoadjuvant immune checkpoint inhibitors (ICI) to explore features associated with complete response to neoadjuvant ICI treatment, which is of great significance in identifying patients who can be exempted from surgery to protect organ function. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2023-10-10 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
|
|
Biomarkers of Pathological Complete Response to Neoadjuvant Immunotherapy in Mismatch Repair Deficiency Colorectal Cancer
|
Clinical Cancer Research
|
10.1158/1078-0432.CCR-23-2213
|
2023
|
| 41237766
|
Paneth-like transition drives resistance to dual targeting of KRAS and EGFR in colorectal cancer
|
Cancer Cell
|
10.1016/j.ccell.2025.10.010
|
2025
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
82272800
|
|
|
| 提交者 |
Yanhong
Deng (dengyanh@mail.sysu.edu.cn)
|
| 提交单位 |
The Sixth Affiliated Hospital of Sun Yat-sen University |
| 提交日期 |
2023-07-31 |