| Accession | PRJCA018741 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Title | liver transplantation | ||||||||||||
| Relevance | Medical | ||||||||||||
| Data types |
Transcriptome or Gene expression
Raw sequence reads Single cell sequencing |
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| Organisms | Rattus | ||||||||||||
| Description | LT models of Lewis-Lewis and F344-Lewis rats were established. Lewis-Lewis rats model served as a control (Syn). F344-Lewis rats were treated with immunosuppressant alone (Allo+IS) or in combination with MSCs (Allo+IS+MSCs). Intrahepatic cell composition particularly immune cells was compared between the groups by single-cell sequencing. Analysis of subclusters, KEGG pathway analysis, and pseudotime trajectory analysis were performed to explore the potential immunoregulatory mechanisms of immunosuppressant alone or combined with MSCs. | ||||||||||||
| Sample scope | Multiisolate | ||||||||||||
| Release date | 2023-11-21 | ||||||||||||
| Grants |
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| Submitter | Haitao Li (lht45182@163.com) | ||||||||||||
| Organization | Mengchao Hepatobiliary Hospital of Fujian Medical University | ||||||||||||
| Submission date | 2023-08-01 |