Accession PRJCA018741
Title liver transplantation
Relevance Medical
Data types Transcriptome or Gene expression
Raw sequence reads
Single cell sequencing
Organisms Rattus
Description LT models of Lewis-Lewis and F344-Lewis rats were established. Lewis-Lewis rats model served as a control (Syn). F344-Lewis rats were treated with immunosuppressant alone (Allo+IS) or in combination with MSCs (Allo+IS+MSCs). Intrahepatic cell composition particularly immune cells was compared between the groups by single-cell sequencing. Analysis of subclusters, KEGG pathway analysis, and pseudotime trajectory analysis were performed to explore the potential immunoregulatory mechanisms of immunosuppressant alone or combined with MSCs.
Sample scope Multiisolate
Release date 2023-11-21
Agency program Grant ID Grant title
Natural Science Foundation of Fujian Province General program 2020J011163
Fujian Provincial Health Bureau 2020CXA054 Medical Innovation program of Fujian Province
Submitter Haitao    Li  (
Organization Mengchao Hepatobiliary Hospital of Fujian Medical University
Submission date 2023-08-01

Project Data

Resource name Description
BioSample (6)  show -
GSA (1) -
CRA012066 Single cell RNA-seq data of rats liver tissue