| 项目编号 |
PRJCA018741 |
| 项目标题 |
liver transplantation |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
Raw sequence reads
Single cell sequencing
|
| 物种名称 |
Rattus
|
| 描述信息 |
LT models of Lewis-Lewis and F344-Lewis rats were established. Lewis-Lewis rats model served as a control (Syn). F344-Lewis rats were treated with immunosuppressant alone (Allo+IS) or in combination with MSCs (Allo+IS+MSCs). Intrahepatic cell composition particularly immune cells was compared between the groups by single-cell sequencing. Analysis of subclusters, KEGG pathway analysis, and pseudotime trajectory analysis were performed to explore the potential immunoregulatory mechanisms of immunosuppressant alone or combined with MSCs. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2023-11-21 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 38143768
|
Immunologic barriers in liver transplantation: a single-cell analysis of the role of mesenchymal stem cells
|
Frontiers in Immunology
|
10.3389/fimmu.2023.1274982
|
2023
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Natural Science Foundation of Fujian Province
|
General program
|
2020J011163
|
|
| Fujian Provincial Health Bureau
|
|
2020CXA054
|
Medical Innovation program of Fujian Province
|
|
|
| 提交者 |
Haitao
Li (lht45182@163.com)
|
| 提交单位 |
Mengchao Hepatobiliary Hospital of Fujian Medical University |
| 提交日期 |
2023-08-01 |
