| Accession | PRJCA018782 | ||||||||||||||||
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| Title | Molecular characterization of long-term glioblastoma survivors | ||||||||||||||||
| Relevance | Medical | ||||||||||||||||
| Data types |
Epigenomics
Exome Transcriptome or Gene expression |
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| Organisms | Homo sapiens | ||||||||||||||||
| Description | Only fewer than 5% GBM patients survive over 5 years and referred as long-term survivors (LTS), yet the underlying molecular background of these LTS are insufficiently understood. Herein, we employed comprehensive whole exome sequencing (WES), RNA-seq and methylation array to delineate molecular landscape of the largest LTS cohort to date. Our cohort consisted of 78 primary GBM patients and were divided into LTS (n = 37) and short-term survivors (STS, OS <= 24 months, n = 41), all confirmed being isocitrate dehydrogenase (IDH)-wildtype. | ||||||||||||||||
| Sample scope | Monoisolate | ||||||||||||||||
| Release date | 2023-08-02 | ||||||||||||||||
| Grants |
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| Submitter | Zhiyong Qin (qinzhiyong@fudan.edu.cn) | ||||||||||||||||
| Organization | Huashan Hospital Fudan University | ||||||||||||||||
| Submission date | 2023-08-02 |
| Resource name | Description |
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| BioSample (211) show | - |