| 项目编号 |
PRJCA018812 |
| 项目标题 |
Neo-antigen Discovery of Cancer Immunotherapy |
| 涉及领域 |
Medical |
| 数据类型 |
Whole genome sequencing
Transcriptome or Gene expression
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Tumor-specific antigens (TSAs) are highly desirable targets for cancer immunotherapy. However, current clinical studies have predominantly focused on neoantigens present in exon regions, while the limited number of TSAs identified from coding regions has impeded the development and application of immunotherapy. Here, we developed a proteogenomic approach that integrates multi-omics data from the whole genome, transcriptome, and immunopeptidome to globally discover TSAs. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2023-10-30 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 39640572
|
Immunogenic peptides putatively from intratumor microbes: Opportunities for colorectal cancer treatment
|
iScience
|
10.1016/j.isci.2024.111338
|
2024
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| No funding support
|
|
|
|
|
|
| 提交者 |
Xuan
DONG (dongxuan@genomics.cn)
|
| 提交单位 |
BGI |
| 提交日期 |
2023-08-03 |
