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项目编号 PRJCA018824
项目标题 Dynamic peripheral blood microRNA expression landscape during the peri-implantation stage in women with successful pregnancy achieved by single frozen-thawed blastocyst transfer
涉及领域 Medical
数据类型 Raw sequence reads
物种名称 Homo sapiens
描述信息 Emerging evidence suggests that miRNAs in peripheral blood have indicative functions in early pregnancy including embryo implantation, and circulating miRNAs are considered to be significant biomarkers due to the informative, stable and non-invasive features. Therefore, the dynamic expression profile of blood miRNAs during WOI could be used to reveal the physiological characteristics of embryo implantation. However, there are no studies reporting the dynamic circulating miRNA expression traits after human embryo begins to invade into endometrium during WOI. In this study, by using miRNA sequence, we firstly seek to depict dynamic circulating miRNA profiles at different sequential time points during human embryo implantation among infertile women who received frozen-thawed embryo transferring (FET) and achieved a live birth. We aim to define the dynamic physiological properties of human embryo implantation before and after human embryo implantation based on plasma miRNA expression landscape.
样品范围 Multiisolate
发布日期 2023-08-23
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
37700872 Dynamic peripheral blood microRNA expression landscape during the peri-implantation stage in women with successful pregnancy achieved by single frozen-thawed blastocyst transfer Human Reproduction Open 10.1093/hropen/hoad034 2023
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
Tangdu Hospital Clinical study poject 2021LCYJ004 Non-invasive miRNomics technology based on artificial intelligence for treatment of recurent implantation failure: a randomized controlled trial
提交者 Xiaohong Wang (wangxh919@fmmu.edu.cn)
提交单位 Tangdu Hospital, Fourth Military Medical University
提交日期 2023-08-04

项目包含数据信息

资源名称 描述
BioSample (170)  show -