项目编号 PRJCA018986
项目标题 Natural Product P57 Induces Hypothermia through Targeting Pyridoxal Kinase
涉及领域 Medical
数据类型 Single cell sequencing
物种名称 Mus musculus
描述信息 Induction of hypothermia during hibernation/torpor enables certain mammals to survive under extreme conditions. Here, we show that a natural product P57 induces hypothermia by targeting pyridoxal kinase and has a potential application in therapeutic hypothermia.
样品范围 Single cell
发布日期 2023-08-14
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
37752106 Natural product P57 induces hypothermia through targeting pyridoxal kinase Nature Communications 10.1038/s41467-023-41435-y 2023
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
National Natural Science Foundation of China (NSFC) 22137002
National Natural Science Foundation of China (NSFC) 21877016
提交者 Guangsen Bao (gsbao21@m.fudan.edu.cn)
提交单位 Fudan University
提交日期 2023-08-11

项目包含数据信息

资源名称 描述
BioSample (3) -
SAMC2999075 snRNA-seq of mus musculus: P57 treatment
SAMC2999074 snRNA-seq of mus musculus: PL treatment
SAMC2999073 snRNA-seq of mus musculus: control
GSA (1) -
CRA012207 P57 and PL play a similar effect on hypothalamus neurons