Accession PRJCA020002
Title Gene regulatory innovations underlying human neocortical diversification
Relevance Medical
Data types Epigenomics
Transcriptome or Gene expression
Genome sequencing
Single cell sequencing
Organisms Homo sapiens
Description To delve into the cellular diversity and spatial arrangement within various adult human neocortical areas, we carried out spatial transcriptomics and conducted single-nucleus multiome analysis, encompassing both snATAC-seq and snRNA-seq from the same cells. The integration of snATAC-seq and snRNA-seq in a joint analysis shed light on the regulatory mechanisms governing the specification and evolutionary aspects of human neocortical areas.
Sample scope Single cell
Release date 2023-09-25
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 82071259
STI2030-Major Projects 2021ZD0200100
The Shanghai Municipal Science and Technology Major Project 2018SHZDZX01
Submitter Ying Zhu (ying_zhu@fudan.edu.cn)
Organization Fudan University
Submission date 2023-09-21

Project Data

Resource name Description