| Accession |
PRJCA020020 |
| Title |
Early-life exercise promotes health aging in mice |
| Relevance |
Medical |
| Data types |
Metabolomics
|
| Organisms |
Mus musculus
|
| Description |
In this study, we investigated whether early-life exercise affects lifespan and health span in C57BL/6J mice and its benefits to multiple organs during aging. Mice in exercise group started swimming at 1 month of age and stopped at 4 month of age (90 minutes per day and 5 days per week). No exercise intervention was conducted in other time. Metabolomics were performed at the age of 4 months,20 months and 24 months to obtain insight into mechanisms that how early-life exercise affects aged mice. |
| Sample scope |
Multiisolate |
| Release date |
2025-05-05 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 40634291
|
Early-life exercise extends healthspan but not lifespan in mice
|
Nature Communications
|
10.1038/s41467-025-61443-4
|
2025
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
2020YFC2002900
|
|
|
|
| Submitter |
Xing
Zhang (lbmed@163.com)
|
| Organization |
Air Force Medical University |
| Submission date |
2023-09-21 |
