| 项目编号 |
PRJCA020107 |
| 项目标题 |
Spatially oraanized tumor-stroma boundary determines the efficacy of immunotherapy in colorectal cancer patients |
| 涉及领域 |
Medical |
| 数据类型 |
Raw sequence reads
Single cell sequencing
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Our work therefore uncovered the black box of how the molecular and cellular spatial structures of tumors determine ICBresponse, raising the possibility of reprogramming tumor-stroma boundary for sensitizing immunotherapies in the majority ofCRCs |
| 样品范围 |
Single cell |
| 发布日期 |
2023-12-30 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 40515555
|
SpatialSNV: A novel method for identifying and analyzing spatially resolved SNVs in tumor microenvironments
|
GigaScience
|
10.1093/gigascience/giaf065
|
2025
|
| 39592630
|
Spatially organized tumor-stroma boundary determines the efficacy of immunotherapy in colorectal cancer patients
|
Nature Communications
|
10.1038/s41467-024-54710-3
|
2024
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
82002628
|
|
|
| 提交者 |
rongxin
zhang (zhangrx@sysucc.org.cn)
|
| 提交单位 |
Sun Yat-sen University Cancer Center |
| 提交日期 |
2023-09-25 |