| 项目编号 |
PRJCA020127 |
| 项目标题 |
The spatiotemporal transcriptome and metabolome landscapes of cotton fiber during initiation and early development: a targeted metabolomics validation |
| 涉及领域 |
Agricultural |
| 数据类型 |
targeted metabolomics
|
| 物种名称 |
Gossypium hirsutum
|
| 描述信息 |
In this study, we profiled the dynamics of transcriptome and metabolome during the early stages of cotton fiber cell development using a combination of spatial transcriptomic, single-cell transcriptomic, and spatial metabolomic analyses. We identified the key genes (e.g., DOX2, KCS19.4, BEE3, and HOS3.7) and metabolites (e.g., L-aspartic acid, O-acetylserine, spermidine, and α-linolenic acid) that may regulate the initiation and early elongation of fiber cells. Finally, knockdown and gain-of-function analyses identified a novel gene, GhBEE3/Gh_A09G062900, crucial in cotton fiber initiation. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2023-09-26 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
|
|
Spatiotemporal transcriptome and metabolome landscapes of cotton fiber during initiation and early development
|
Nature Communications
|
10.1038/s41467-025-55869-z
|
2025
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Key Research and Development Program
|
|
2021YFF1000100
|
|
| National Key Research and Development Program
|
|
2022YFD1200300
|
|
|
| 提交者 |
xuwu
sun (sunxuwussd@sina.com)
|
| 提交单位 |
State Key Laboratory of Cotton Biology, State Key Laboratory of Crop Stress Adaptation and Improvement, Key Laboratory of Plant Stress Biology, School of Life Sciences, Henan University |
| 提交日期 |
2023-09-26 |