| 项目编号 | PRJCA020175 | ||||||||||||
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| 项目标题 | a multi-cancer detection and localization approach using circulating tumor DNA methylation markers | ||||||||||||
| 涉及领域 | Medical | ||||||||||||
| 数据类型 | Genome sequencing | ||||||||||||
| 物种名称 | Homo sapiens | ||||||||||||
| 描述信息 | We performed enzymatic conversion-based targeted methylation sequencing on plasma cfDNA samples collected from a clinical cohort of 500 healthy controls and 733 cancer patients with seven types of cancer (breast, colorectum, esophagus, stomach, liver, lung, and pancreas) and randomly divided these samples into a training cohort and a testing cohort. An independent validation cohort of 143 healthy controls, 79 liver cancer patients and 100 stomach cancer patients were recruited to validate the generalizability of our approach. | ||||||||||||
| 样品范围 | Multiisolate | ||||||||||||
| 发布日期 | 2023-10-18 | ||||||||||||
| 出版信息 |
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| 项目资金来源 |
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| 提交者 | Chunguang Li (lcg_gc@163.com) | ||||||||||||
| 提交单位 | Zhongnan Hospital of Wuhan University | ||||||||||||
| 提交日期 | 2023-09-27 |
| 资源名称 | 描述 |
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| BioSample (1555) show | - |