Accession |
PRJCA020227 |
Title |
The single-cell Atlas of Cellular Heterogeneity and The Immunosuppressive Microenvironment of Brain Metastasis from laryngeal squamous cell carcinoma |
Relevance |
Medical |
Data types |
Single cell sequencing
|
Organisms |
Homo sapiens
|
Description |
Brain metastasis (BM) from laryngeal squamous cell carcinoma (LSCC) is rare but with poor prognosis. Here, we reported a rare case with two BMs from LSCC, which were removed surgically. Despite treated with radiotherapy, chemotherapy and a PD-1 inhibitor, a new brain lesion was found and resected again. The three lesions were analyzed with single-cell RNA-seq. |
Sample scope |
Single cell |
Release date |
2023-09-30 |
Grants |
Agency |
program |
Grant ID |
Grant title |
National Natural Science Foundation of China (NSFC)
|
General Program
|
82372624
|
Downregulation of plakophilin 2 m6A level promotes invasiveness of growth hormone secreting pituitary adenomas
|
|
Submitter |
Xiaobing
Jiang (jiangxiaob1@sysucc.org.cn)
|
Organization |
Sun Yat-sen University Cancer Center |
Submission date |
2023-09-30 |