| 项目编号 |
PRJCA020227 |
| 项目标题 |
The single-cell Atlas of Cellular Heterogeneity and The Immunosuppressive Microenvironment of Brain Metastasis from laryngeal squamous cell carcinoma |
| 涉及领域 |
Medical |
| 数据类型 |
Single cell sequencing
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Brain metastasis (BM) from laryngeal squamous cell carcinoma (LSCC) is rare but with poor prognosis. Here, we reported a rare case with two BMs from LSCC, which were removed surgically. Despite treated with radiotherapy, chemotherapy and a PD-1 inhibitor, a new brain lesion was found and resected again. The three lesions were analyzed with single-cell RNA-seq. |
| 样品范围 |
Single cell |
| 发布日期 |
2023-09-30 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 39085744
|
Single-cell atlas profiling revealed cellular characteristics and dynamic changes after PD-1 blockade therapy of brain metastases from laryngeal squamous cell carcinoma
|
Molecular and Cellular Biochemistry
|
10.1007/s11010-024-05064-3
|
2024
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
82372624
|
Downregulation of plakophilin 2 m6A level promotes invasiveness of growth hormone secreting pituitary adenomas
|
|
|
| 提交者 |
Xiaobing
Jiang (jiangxiaob1@sysucc.org.cn)
|
| 提交单位 |
Sun Yat-sen University Cancer Center |
| 提交日期 |
2023-09-30 |
