Accession PRJCA020227
Title The single-cell Atlas of Cellular Heterogeneity and The Immunosuppressive Microenvironment of Brain Metastasis from laryngeal squamous cell carcinoma
Relevance Medical
Data types Single cell sequencing
Organisms Homo sapiens
Description Brain metastasis (BM) from laryngeal squamous cell carcinoma (LSCC) is rare but with poor prognosis. Here, we reported a rare case with two BMs from LSCC, which were removed surgically. Despite treated with radiotherapy, chemotherapy and a PD-1 inhibitor, a new brain lesion was found and resected again. The three lesions were analyzed with single-cell RNA-seq.
Sample scope Single cell
Release date 2023-09-30
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) General Program 82372624 Downregulation of plakophilin 2 m6A level promotes invasiveness of growth hormone secreting pituitary adenomas
Submitter Xiaobing    Jiang  (jiangxiaob1@sysucc.org.cn)
Organization Sun Yat-sen University Cancer Center
Submission date 2023-09-30

Project Data

Resource name Description