| 项目编号 |
PRJCA020288 |
| 项目标题 |
Screening and Identification of Personalized Neoantigens in Prostate Cancer |
| 涉及领域 |
Medical |
| 数据类型 |
Exome
Transcriptome or Gene expression
Genome sequencing
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
In this study, we intend to conduct whole-genome and transcriptome analysis of tumor tissues and blood samples from prostate cancer patients. Using bioinformatics methods, we aim to identify personalized, patient-specific neoantigens in order to better understand the immunological characteristics of the tumors. Furthermore, we will assess whether the selected neoantigens possess sufficient immunogenicity to elicit a strong immune response, thus contributing to the induction of a lasting anti-cancer immune response. This research is aimed at screening and identifying personalized neoantigens for prostate cancer, which will help in designing cancer vaccines and immunotherapy strategies for patients. It will also provide insights into the potential of immunotherapy in prostate cancer and offer crucial information for the development of future immunotherapeutic strategies. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2023-10-06 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
82150208
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82173690
|
|
|
|
| 提交者 |
shiliang
Li (slli@hsc.ecnu.edu.cn)
|
| 提交单位 |
East China Normal University, Innovation Center for AI and Drug Discovery |
| 提交日期 |
2023-10-06 |
