Accession PRJCA020550
Title Advances in the regulation of metabolic associated fatty liver disease by intermittent hypoxia
Relevance Medical
Data types Raw sequence reads
Organisms Homo sapiens
Description Obstructive sleep apnea (OSA) is an independent risk factor for metabolic dysfunction-associated fatty liver disease (MAFLD). Copper deficiency can disrupt redox homeostasis and lipid metabolism, contributing to the development of MAFLD. Here, we investigated what role of hepatic copper deficiency plays in OSA-associated MAFLD and explore the possible underlying mechanism(s)
Sample scope Multiisolate
Release date 2024-08-04
Publication
PubMed ID Article title Journal name DOI Year
38963329 Intermittent hypoxia exacerbates metabolic dysfunction-associated fatty liver disease by aggravating hepatic copper deficiency-induced ferroptosis Faseb Journal 10.1096/fj.202400840R 2024
Grants
Agency program Grant ID Grant title
the Key Laboratory of Advanced Interdisciplinary Studies Center grants from the Joint Funding from Guangzhou science and technology bureau and the First Affiliated Hospital of Guangzhou Medical University No.202102010319 Advances in the regulation of metabolic associated fatty liver disease by intermittent hypoxia
Submitter Ruhua Wang (oct5255@126.com)
Organization the First Affiliated Hospital of Guangzhou Medical University
Submission date 2023-10-17

Project Data

Resource name Description