Accession |
PRJCA020550 |
Title |
Advances in the regulation of metabolic associated fatty liver disease by intermittent hypoxia |
Relevance |
Medical |
Data types |
Raw sequence reads
|
Organisms |
Homo sapiens
|
Description |
Obstructive sleep apnea (OSA) is an independent risk factor for metabolic dysfunction-associated fatty liver disease (MAFLD). Copper deficiency can disrupt redox homeostasis and lipid metabolism, contributing to the development of MAFLD. Here, we investigated what role of hepatic copper deficiency plays in OSA-associated MAFLD and explore the possible underlying mechanism(s) |
Sample scope |
Multiisolate |
Release date |
2024-08-04 |
Publication |
PubMed ID |
Article title |
Journal name |
DOI |
Year |
38963329
|
Intermittent hypoxia exacerbates metabolic dysfunction-associated fatty liver disease by aggravating hepatic copper deficiency-induced ferroptosis
|
Faseb Journal
|
10.1096/fj.202400840R
|
2024
|
|
Grants |
Agency |
program |
Grant ID |
Grant title |
the Key Laboratory of Advanced Interdisciplinary Studies Center
|
grants from the Joint Funding from Guangzhou science and technology bureau and the First Affiliated Hospital of Guangzhou Medical University
|
No.202102010319
|
Advances in the regulation of metabolic associated fatty liver disease by intermittent hypoxia
|
|
Submitter |
Ruhua
Wang (oct5255@126.com)
|
Organization |
the First Affiliated Hospital of Guangzhou Medical University |
Submission date |
2023-10-17 |