| 项目编号 |
PRJCA020698 |
| 项目标题 |
Effects of early fecal microbiota transplantation on gut microbiota composition and abdominal fat deposition level in chickens |
| 涉及领域 |
Agricultural |
| 数据类型 |
Metagenome
Metabolome, amplicon
|
| 物种名称 |
Gallus gallus
|
| 描述信息 |
Abdominal fat deposition (AFD) in chickens is closely related to the gut microecological balance. In this study, the gut microbiota from high-AFD chickens was transplanted into the same strain of 0-day-old chicks via fecal microbiota transplantation (FMT). The FTM from chickens with high AFD had no obvious effects on growth traits, adult body weight, carcass weight, abdominal fat weight, and abdominal fat percentage, but did reduce the coefficient of variation of AFD traits. FMT significantly decreased cecal microbiome richness, changed the microbiota structure, and regulated the biological functions associated with energy metabolism and fat synthesis. Additionally, the cecal metabolite composition and metabolic function of FMT recipient chickens were also significantly altered from those of the controls. Transplantation of high-AFD chicken gut microbiota promoted fatty acid elongation and biosynthesis and reduced the metabolism of vitamins, steroids, and carbohydrates in the cecum. These findings provide insights into the mechanisms by which chicken gut microbiota affect host metabolic profiles and fat deposition. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2024-04-01 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 38260901
|
Early fecal microbiota transplantation from high abdominal fat chickens affects recipient cecal microbiome and metabolism
|
Frontiers in Microbiology
|
10.3389/fmicb.2023.1332230
|
2024
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Department of Science and Technology of Guangdong Province
|
|
2019B030301010
|
the Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breed
|
| Qingyuan city Science and Technology Bureau
|
|
2021SXJM011
|
the Science and Technology Foundation of Qingyuan Cit
|
|
| 提交者 |
jiani
song (1151957975@qq.com)
|
| 提交单位 |
Foshan University |
| 提交日期 |
2023-10-13 |