| 项目编号 | PRJCA020788 | ||||||||||||||||||||||||
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| 项目标题 | The extracellular-matrix-remodeling capability exposes therapeutic vulnerability in a subset of clear cell renal cell carcinoma with vena caval tumor thrombus | ||||||||||||||||||||||||
| 涉及领域 | Medical | ||||||||||||||||||||||||
| 数据类型 |
Exome
Transcriptome or Gene expression Single cell sequencing |
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| 物种名称 |
Homo sapiens
Mus |
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| 描述信息 | Tumor thrombus (TT) of ccRCC is a molecularly diverse disease with heterogeneous clinical outcomes. Development and progression of higher-level TT remains a clinical problem, without a clear understanding of what drives immune escape and tumor progression. Here, we comprehensively performed multiomics integrated analysis to dissect the two distinct TT modes and perform comparative analysis on both cellular composition and functional phenotype between TT1 and TT2 tumors. | ||||||||||||||||||||||||
| 样品范围 | Multiisolate | ||||||||||||||||||||||||
| 发布日期 | 2025-07-03 | ||||||||||||||||||||||||
| 出版信息 |
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| 项目资金来源 |
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| 提交者 | Weimin ci (ciwm@big.ac.cn) | ||||||||||||||||||||||||
| 提交单位 | Beijing Institute of Genomics, Chinese Academy of Sciences | ||||||||||||||||||||||||
| 提交日期 | 2023-10-25 |