| 项目编号 |
PRJCA020796 |
| 项目标题 |
Distinct immune features in the partial remission phase of type 1 diabetes identified by single-cell RNA sequencing and functional analysis |
| 涉及领域 |
Medical |
| 数据类型 |
Single cell sequencing
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
To better understand the heterogeneity across the different stages of T1D, scRNA-seq was performed to interrogate the transcriptomic status of the peripheral immune cells from T1D individuals. In total, 12 cases were enrolled, including 5 new-onset cases with T1D (New), 4 cases during PR with T1D (PR), and 3 healthy donors (HD). |
| 样品范围 |
Single cell |
| 发布日期 |
2024-09-09 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 39406740
|
TGF-β-mediated crosstalk between TIGIT+ Tregs and CD226+ CD8+ T cells in the progression and remission of type 1 diabetes
|
Nature Communications
|
10.1038/s41467-024-53264-8
|
2024
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
82070812
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
82170795
|
|
|
|
| 提交者 |
Xia
Li (lixia@csu.edu.cn)
|
| 提交单位 |
The second Xiangya hospital of central south university |
| 提交日期 |
2023-10-26 |
