| Accession |
PRJCA020910 |
| Title |
Single-cell atlas of human cell lines |
| Relevance |
Model organism |
| Data types |
Epigenomics
Transcriptome or Gene expression
Single cell sequencing
|
| Organisms |
Homo sapiens
|
| Description |
Single-cell atlas of human cell lines generated single-cell transcriptome and single-cell chromatin accessibility data of dozens of cancer cell lines and 2 normal cell lines to illustrate both transcriptional and epigenetic heterogeneity within different cell lines. The plasticity of transcriptomic heterogeneity is demonstrated by lineage tracing and hypoxia treatment. |
| Sample scope |
Monoisolate |
| Release date |
2023-11-14 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 38071219
|
Single cell multi-omics reveal intra-cell-line heterogeneity across human cancer cell lines
|
Nature Communications
|
10.1038/s41467-023-43991-9
|
2023
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China
|
|
32100613
|
|
| National Key Research and Development Program of China
|
|
021YFF1201000
|
|
| Shenzhen Science and Technology Program
|
|
KQTD20180411143432337
|
|
| Shenzhen Science and Technology Program
|
|
JCYJ20210324104605014
|
|
| Shenzhen Science and Technology Program
|
|
JCYJ20190809154407564
|
|
| Shenzhen Key Laboratory of Gene Regulation and Systems Biolog
|
|
ZDSYS20200811144002008
|
|
| Guangdong Basic and Applied Basic Research Foundation
|
|
2021A1515110832
|
|
| Guangdong-Hong Kong Joint Laboratory on Immunological and Genetic Kidney Diseases
|
|
019B121205005
|
|
| Shenzhen Key Laboratory of Single-Cell Omics
|
|
ZDSYS20190902093613831
|
|
|
|
| External link |
| External link |
Link description |
| https://db.cngb.org/cdcp/scatlashcl/ |
Single-cell atlas of human cell lines generated single-cell transcriptome and single-cell chromatin accessibility data of dozens of cancer cell lines and 2 normal cell lines to illustrate heterogeneity within different cell lines. |
|
|
| Submitter |
liang
wu (wuliang@genomics.cn)
|
| Organization |
BGI-Shenzhen |
| Submission date |
2023-10-31 |
