| Accession |
PRJCA021017 |
| Title |
The mechanism and function of H3K79 methylation in regulating transcription elongation rate |
| Relevance |
Epigenetic |
| Data types |
Transcriptome or Gene expression
Raw sequence reads
Genome sequencing
|
| Organisms |
Homo sapiens
|
| Description |
This study used mass spectrometry technology to systematically identify the recognition proteins of H3K79 modification, used ChIP-seq to analyze the molecular mechanism by which H3K79 methylation regulates transcription elongation rate, and used transcriptome sequencing to analyze the impact of blocked transcription elongation on RNA processing.Finally, we focused on the impact of H3K79 methylation on host cell transcription under viral infection. |
| Sample scope |
Monoisolate |
| Release date |
2024-06-11 |
| Publication |
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
31970619
|
|
| National Natural Science Foundation of China (NSFC)
|
|
32171289
|
|
| National Key Research and DevelopmentProgram of China
|
|
2021YFA1100500
|
|
|
|
| Submitter |
Liang
Chen (liang_chen@whu.edu.cn)
|
| Organization |
Wuhan University |
| Submission date |
2023-11-03 |
