项目编号 PRJCA021037
项目标题 Integrative multi-omics landscape of adult diffuse glioma
涉及领域 Medical
数据类型 Exome
Transcriptome or Gene expression
物种名称 Homo sapiens
描述信息 Diffuse glioma is the most common malignant brain tumor in adults with limited therapeutic options. We integrated genomics, transcriptomics, proteomics, and phosphoproteomics from 339 adult-type diffuse gliomas in two Chinese cohorts. The integrative proteogenomic analysis would further capture the true diversity and complexity of glioma carcinogenesis and provide a comprehensive biological understanding spanning genomic boundaries.
样品范围 Multiisolate
发布日期 2025-02-20
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
Machine Learning Model on Multi-Omics Data Enables Risk Stratification and Identifies Molecular Heterogeneity and Therapeutic Targets in Glioblastoma Research Square 10.21203/rs.3.rs-7510857/v1 2025
39845415 IDH-mutant glioma risk stratification via whole slide images: identifying pathological feature associations iScience 10.1016/j.isci.2024.111605 2025
40222975 Multimodal fusion of radio-pathology and proteogenomics identify integrated glioma subtypes with prognostic and therapeutic opportunities Nature Communications 10.1038/s41467-025-58675-9 2025
Machine Learning Model on Multi-Omics Data Enables Risk Stratification and Identifies Molecular Heterogeneity and Therapeutic Targets in Glioblastoma Research Square 10.21203/rs.3.rs-7510857/v1 2025
41377462 P4HB regulates tumor-associated macrophage polarization and chemotaxis by enhancing IL-6 cytokine secretion in glioblastoma Annals of Medicine and Surgery (2012) 10.1097/MS9.0000000000004049 2025
40335825 MRI-based machine learning reveals proteasome subunit PSMB8-mediated malignant glioma phenotypes through activating TGFBR1/2-SMAD2/3 axis Molecular Biomedicine 10.1186/s43556-025-00268-5 2025
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
National Natural Science Foundation of China (NSFC) 31870902
提交者 Zhenyu Zhang (fcczhangzy1@zzu.edu.cn)
提交单位 The First Affiliated Hospital of Zhengzhou University
提交日期 2023-11-04

项目包含数据信息

资源名称 描述
BioSample (378)  show -