| Accession |
PRJCA021043 |
| Title |
Investigation of RBM10 mutation and its associations with clinical and molecular characteristics in EGFR-mutant and EGFR-wildtype lung adenocarcinoma |
| Relevance |
Medical |
| Data types |
Variation
|
| Organisms |
Homo sapiens
|
| Description |
We comprehensively investigated RBM10 mutations in a Chinese cohort with LUAD. Tumor sequencing data from 2,848 Chinese patients with LUAD were retrospectively reviewed and analyzed.The associations of RBM10 mutation with clinical and molecular characteristics were assessed. An external cohort of 182 patients with LUAD who received PD-1 inhibitor were used to investigate the association of RBM10 mutation with clinical outcomes upon immunotherapy. |
| Sample scope |
Multiisolate |
| Release date |
2023-11-24 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 38912481
|
Investigation of RBM10 mutation and its associations with clinical and molecular characteristics in EGFR-mutant and EGFR-wildtype lung adenocarcinoma
|
Heliyon
|
10.1016/j.heliyon.2024.e32287
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| The Shenzhen Science and Technology Program
|
|
RCJC20200714114436049
|
|
| Cancer Hospital, Chinese Academy of Medical Sciences, Shenzhen Center/Shenzhen Cancer Hospital Research Project
|
|
SZ2020ZD006
|
|
|
|
| Submitter |
Shi
Jin (catherine-jinshi@163.com)
|
| Organization |
National cancer center/National clinical research center for cancer/Cancer Hospital&Shenzhen Hospital,Chinese Academy of medical sciences and Peking Union Medical College,Shenzhen |
| Submission date |
2023-11-03 |
