项目编号

PRJCA021396

项目标题

RNA-seq and H3K4me3/H3K27ac histone modification CUT&Tag-seq of mouse embryonic tail tip tissue

涉及领域

Model organism

数据类型

Epigenomics
Transcriptome or Gene expression

物种名称

Mus musculus

描述信息

A temporal series of RNA-seq and H3K4me3/H3K27ac histone modification CUT&Tag-seq was employed to profile the gene expression and chromatinic state dynamics associated with the progress of mouse embryonic tail morphogenesis. Based on temporal (and spatial) disparity analyses, the candidate genes and cis-regulatory elements involved in tail development could be revealed, supplying fundamental and exploitable datasets for the researches to elucidate the complex genetic mechanisms responsible for the formation, and evolutionary developmental divergence, of the vertebrate/mammalian tail. Given the period (E10.5 ~ E15.5) of the embryonic tail morphogenesis in C57BL/6J mice, six consecutive stages (E10.5, E11.5, E12.5, E13.5, E14.5 and E15.5) were designed to sample the two positions of tail tip tissues, termed T1 (terminal, 1 mm, containing the tail bud area) and T2 (proximally contiguous, 1 mm, as a control) respectively, for RNA-seq. T1 region was sampled at three stages (E10.5, E12.5 and E14.5) for the CUT&Tag-seq of H3K4me3 and H3K27ac histone modifications. Three biological replicates were prepared for all samplings.

样品范围

Monoisolate

发布日期

2023-11-18

项目资金来源

机构	项目类型	授权项目ID
Chinese Academy of Sciences (CAS)	Light of West China Program	xbzg-zdsys-202213
Department of Science and Technology of Yunnan Province	Yunnan Applied Basic Research Project	202305AH340006
Department of Science and Technology of Yunnan Province	Yunnan Applied Basic Research Project	2019FI010
Department of Science and Technology of Yunnan Province	Yunnan Applied Basic Research Project	2019FA008
Department of Science and Technology of Yunnan Province	Yunnan Applied Basic Research Project	2019FJ003

提交者

Wandong Bao (baowandong@mail.kiz.ac.cn)

提交单位

Kunming Institute of Zoology, Chinese Academy of Sciences

提交日期

2023-11-16

项目包含数据信息

资源名称	描述
BioSample (54) show	-
SAMC3180210	T1 region of tail tip at E14.5, replicate 3, for H3K27ac CUT&Tag-seq
SAMC3180209	T1 region of tail tip at E14.5, replicate 2, for H3K27ac CUT&Tag-seq
SAMC3180208	T1 region of tail tip at E14.5, replicate 1, for H3K27ac CUT&Tag-seq
SAMC3180207	T1 region of tail tip at E12.5, replicate 3, for H3K27ac CUT&Tag-seq
SAMC3180206	T1 region of tail tip at E12.5, replicate 2, for H3K27ac CUT&Tag-seq
SAMC3180205	T1 region of tail tip at E12.5, replicate 1, for H3K27ac CUT&Tag-seq
SAMC3180204	T1 region of tail tip at E10.5, replicate 3, for H3K27ac CUT&Tag-seq
SAMC3180203	T1 region of tail tip at E10.5, replicate 2, for H3K27ac CUT&Tag-seq
SAMC3180202	T1 region of tail tip at E10.5, replicate 1, for H3K27ac CUT&Tag-seq
SAMC3180201	T1 region of tail tip at E14.5, replicate 3, for H3K4me3 CUT&Tag-seq
SAMC3180200	T1 region of tail tip at E14.5, replicate 2, for H3K4me3 CUT&Tag-seq
SAMC3180199	T1 region of tail tip at E14.5, replicate 1, for H3K4me3 CUT&Tag-seq
SAMC3180198	T1 region of tail tip at E12.5, replicate 3, for H3K4me3 CUT&Tag-seq
SAMC3180197	T1 region of tail tip at E12.5, replicate 2, for H3K4me3 CUT&Tag-seq
SAMC3180196	T1 region of tail tip at E12.5, replicate 1, for H3K4me3 CUT&Tag-seq
SAMC3180195	T1 region of tail tip at E10.5, replicate 3, for H3K4me3 CUT&Tag-seq
SAMC3180194	T1 region of tail tip at E10.5, replicate 2, for H3K4me3 CUT&Tag-seq
SAMC3180193	T1 region of tail tip at E10.5, replicate 1, for H3K4me3 CUT&Tag-seq
SAMC3180192	T2 region of tail tip at E15.5, replicate 3, for RNA-seq
SAMC3180191	T2 region of tail tip at E15.5, replicate 2, for RNA-seq
SAMC3180190	T2 region of tail tip at E15.5, replicate 1, for RNA-seq
SAMC3180189	T2 region of tail tip at E14.5, replicate 3, for RNA-seq
SAMC3180188	T2 region of tail tip at E14.5, replicate 2, for RNA-seq
SAMC3180187	T2 region of tail tip at E14.5, replicate 1, for RNA-seq
SAMC3180186	T2 region of tail tip at E13.5, replicate 3, for RNA-seq
SAMC3180185	T2 region of tail tip at E13.5, replicate 2, for RNA-seq
SAMC3180184	T2 region of tail tip at E13.5, replicate 1, for RNA-seq
SAMC3180183	T2 region of tail tip at E12.5, replicate 3, for RNA-seq
SAMC3180182	T2 region of tail tip at E12.5, replicate 2, for RNA-seq
SAMC3180181	T2 region of tail tip at E12.5, replicate 1, for RNA-seq
SAMC3180180	T2 region of tail tip at E11.5, replicate 3, for RNA-seq
SAMC3180179	T2 region of tail tip at E11.5, replicate 2, for RNA-seq
SAMC3180178	T2 region of tail tip at E11.5, replicate 1, for RNA-seq
SAMC3180177	T2 region of tail tip at E10.5, replicate 3, for RNA-seq
SAMC3180176	T2 region of tail tip at E10.5, replicate 2, for RNA-seq
SAMC3180175	T2 region of tail tip at E10.5, replicate 1, for RNA-seq
SAMC3180174	T1 region of tail tip at E15.5, replicate 3, for RNA-seq
SAMC3180173	T1 region of tail tip at E15.5, replicate 2, for RNA-seq
SAMC3180172	T1 region of tail tip at E15.5, replicate 1, for RNA-seq
SAMC3180171	T1 region of tail tip at E14.5, replicate 3, for RNA-seq
SAMC3180170	T1 region of tail tip at E14.5, replicate 2, for RNA-seq
SAMC3180169	T1 region of tail tip at E14.5, replicate 1, for RNA-seq
SAMC3180168	T1 region of tail tip at E13.5, replicate 3, for RNA-seq
SAMC3180167	T1 region of tail tip at E13.5, replicate 2, for RNA-seq
SAMC3180166	T1 region of tail tip at E13.5, replicate 1, for RNA-seq
SAMC3180165	T1 region of tail tip at E12.5, replicate 3, for RNA-seq
SAMC3180164	T1 region of tail tip at E12.5, replicate 2, for RNA-seq
SAMC3180163	T1 region of tail tip at E12.5, replicate 1, for RNA-seq
SAMC3180162	T1 region of tail tip at E11.5, replicate 3, for RNA-seq
SAMC3180161	T1 region of tail tip at E11.5, replicate 2, for RNA-seq
SAMC3180160	T1 region of tail tip at E11.5, replicate 1, for RNA-seq
SAMC3180159	T1 region of tail tip at E10.5, replicate 3, for RNA-seq
SAMC3180158	T1 region of tail tip at E10.5, replicate 2, for RNA-seq
SAMC3180157	T1 region of tail tip at E10.5, replicate 1, for RNA-seq
GSA (1)	-
CRA013613	RNA-seq and H3K4me3/H3K27ac histone modification CUT&Tag-seq of mouse embryonic tail tip tissue