| 项目编号 |
PRJCA021646 |
| 项目标题 |
Identification of Novel Non-coding Genetic Elements of Lung Cancer Using Whole Genome Sequencing in Chinese |
| 涉及领域 |
Genetic epidemiology |
| 数据类型 |
Whole genome sequencing
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
We performed an extensive WGS study in a total of 13,722 Chinese individuals with a particular emphasis on non-coding regulation. In the discovery stage, we sequenced the whole genome for 11,058 Chinese subjects and performed a full minor allele frequency (MAF) spectrum scan on lung cancer-associated variants and genes. We sequenced additional 3,055 Chinese subjects to verify the findings. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2024-06-24 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 40050692
|
Identification of potential susceptibility loci for non-small cell lung cancer through whole genome sequencing in circadian rhythm genes
|
Scientific Reports
|
10.1038/s41598-025-92083-9
|
2025
|
| 40205015
|
Transcriptome-wide association study of alternative polyadenylation identifies susceptibility genes in non-small cell lung cancer
|
Oncogene
|
10.1038/s41388-025-03338-8
|
2025
|
| 40783572
|
Non-coding genetic elements of lung cancer identified using whole genome sequencing in 13,722 Chinese
|
Nature Communications
|
10.1038/s41467-025-62459-6
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Healthy Zhejiang One Million People Cohort
|
|
K-20230085
|
|
| Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang
|
|
2019R01007
|
|
| Key Research and Development Program of Zhejiang Province
|
|
2020C03002
|
|
|
|
| 提交者 |
xifeng
Wu (xifengw@zju.edu.cn)
|
| 提交单位 |
The Second Affiliated Hospital of Zhejiang University School of Medicine |
| 提交日期 |
2023-11-29 |
