| Accession |
PRJCA021815 |
| Title |
OA cartilage eQTL |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
Raw sequence reads
|
| Organisms |
Homo sapiens
|
| Description |
Cartilage is an important component of the joint and plays a critical role in the pathogenesis of osteoarthritis (OA). The study of gene expression regulation mechanism in cartilage is of great importance to elucidate the genetic mechanism of OA. However, the regulatory landscape of gene expression in cartilage remains poorly understood, due to the absence of large-scale resources. Here, we aimed to fill this knowledge gap by integrating genomics with transcriptomics features of human knee cartilage from up to 204 OA patients. |
| Sample scope |
Multiisolate |
| Release date |
2025-05-02 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 40577937
|
Genetic transcriptional regulation profiling of cartilage reveals pathogenesis of osteoarthritis
|
EBioMedicine
|
10.1016/j.ebiom.2025.105821
|
2025
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
32170616
|
|
|
|
| Submitter |
Tie-Lin
Yang (yangtielin@xjtu.edu.cn)
|
| Organization |
Xi'an Jiaotong University |
| Submission date |
2023-12-04 |
