| 项目编号 |
PRJCA022071 |
| 项目标题 |
Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis |
| 涉及领域 |
Medical |
| 数据类型 |
Whole genome sequencing
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Previously, we isolated CRC stem cells from patient samples and screened the gene expression in CRC stem cells. The results showed that DKK4 highly expressed in CRC stem cells and greatly decreased its expression in cancer cells derived from the differentiation of CRC stem cells. The distinctive DKK4 expressing patterns in CRC cells drive us to address roles of DKK4, an inhibitor of Wnt/beta-catenin signalling pathway, in CRC formation and progression. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2023-12-14 |
| 出版信息 |
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
81972592
|
|
| the 1.3.5 project for disciplines of excellence of West China Hospital
|
|
ZYGD20007
|
|
|
|
| 提交者 |
Xue
Li (lixue-87@163.com)
|
| 提交单位 |
West China Hospital of Sichuan University |
| 提交日期 |
2023-12-14 |
