| 项目编号 |
PRJCA022185 |
| 项目标题 |
Single-cell RNA-seq profiling the heterogeneity of tumor cells and microenvironments in different pathological endometrial cancer |
| 涉及领域 |
Medical |
| 数据类型 |
Single cell sequencing
|
| 物种名称 |
|
| 描述信息 |
To better explore the specific characteristics of pathogenesis and tumor microenvironment of different EC samples with different pathological types, we performed scRNA-seq on 18 patients. We comprehensively revealed the heterogeneity in percentage, functional status and cell-cell communication of different cell subpopulations within identified malignant epithelial cells, NK_T cells, fibroblasts, macrophages and endothelial cells (ECs) using the single-cell expression atlas and experimental methods in vitro. |
| 样品范围 |
Single cell |
| 发布日期 |
2025-12-19 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 39112478
|
Single-cell transcriptome profiles the heterogeneity of tumor cells and microenvironments for different pathological endometrial cancer and identifies specific sensitive drugs
|
Cell Death & Disease
|
10.1038/s41419-024-06960-8
|
2024
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Henan Province Medical Science and Technology Research Plan Provincial and Ministerial Co-construction Project
|
|
SBGJ202302075
|
|
| Health Commission of Henan Province
|
|
222300420091
|
|
| Scientific Research and Innovation Team of The First Affiliated Hospital of Zhengzhou University
|
|
ZYCXTD2023004
|
|
|
|
| 提交者 |
Fang
Ren (renfang@foxmail.com)
|
| 提交单位 |
The First Affiliated Hospital of Zhengzhou University |
| 提交日期 |
2023-12-19 |
