Accession PRJCA022305
Title Differentiated adaptative genetic architecture and language-related demographical history in South China inferred from 619 genomes from 56 populations
Relevance Evolution
Data types Targeted Locus (Loci)
Organisms Homo sapiens
Description The underrepresentation of human genomic resources from Southern Chinese populations limited their health equality in the precision medicine era and complete understanding of their genetic formation, admixture and adaptive features. Besides, linguistical and genetic evidence supported the controversial hypothesis of their origin processes. One hotspot case was from the Chinese Guangxi Pinghua Han people (GPH), whose language was significantly similar to Southern Chinese dialects but whose uniparental gene pool was phylogenetically associated with the indigenous Tai-Kadai (TK) people. Here, we analyzed genome-wide SNP data in 619 people from four language families and 56 geographically different populations, in which 261 people from 21 geographically distinct populations were first reported here.
Sample scope Monoisolate
Release date 2024-02-21
Publication
PubMed ID Article title Journal name DOI Year
38448908 Differentiated adaptative genetic architecture and language-related demographical history in South China inferred from 619 genomes from 56 populations BMC Biology 10.1186/s12915-024-01854-9 2024
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) Young Scientists Fund 82202078 Forensic exploratory study of high-resolution Y-SNP-STR co-typing in complex pedigree searches and paternal ancestry inference
Submitter Guanglin He (Guanglinhescu@163.com)
Organization Institute of Rare Diseases, West China Hospital of Sichuan University
Submission date 2023-12-22

Project Data

Resource name Description