| Accession |
PRJCA022307 |
| Title |
Malaria resistance-related biological adaptation and complex evolutionary footprints inferred from one integrative Tai-Kadai-related genomic resource |
| Relevance |
Evolution |
| Data types |
Targeted Locus (Loci)
|
| Organisms |
Homo sapiens
|
| Description |
Pathogen-host adaptative interaction and complex population demographical processes, including admixture, drift, and Darwen selection, have considerably shaped the Neolithic-to-Modern Western Eurasian population structure and genetic susceptibility to modern human diseases. However, the genetic footprints of evolutionary events in East Asia remain unknown due to the underrepresentation of genomic diversity and the design of large-scale population studies. We reported one aggregated database of genome-wide-SNP variations from 796 Tai-Kadai (TK) genomes, including Bouyei first reported here, to explore the genetic history, population structure, and biological adaptative features of TK people from Southern China and Southeast Asia. We found geography-related population substructure among TK people using the state-of-the-art population genetic structure reconstruction techniques based on the allele frequency spectrum and haplotype-resolved phased fragments. |
| Sample scope |
Monoisolate |
| Release date |
2024-04-23 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
|
|
Malaria resistance-related biological adaptation and complex evolutionary footprints inferred from one integrative Tai-Kadai-related genomic resource
|
Heliyon
|
10.1016/j.heliyon.2024.e29235
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
Young Scientists Fund
|
82202078
|
Forensic exploratory study of high-resolution Y-SNP-STR co-typing in complex pedigree searches and paternal ancestry inference
|
|
|
| Submitter |
Guanglin
He (Guanglinhescu@163.com)
|
| Organization |
Institute of Rare Diseases, West China Hospital of Sichuan University |
| Submission date |
2023-12-22 |
