| 项目编号 |
PRJCA022307 |
| 项目标题 |
Malaria resistance-related biological adaptation and complex evolutionary footprints inferred from one integrative Tai-Kadai-related genomic resource |
| 涉及领域 |
Evolution |
| 数据类型 |
Targeted Locus (Loci)
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Pathogen-host adaptative interaction and complex population demographical processes, including admixture, drift, and Darwen selection, have considerably shaped the Neolithic-to-Modern Western Eurasian population structure and genetic susceptibility to modern human diseases. However, the genetic footprints of evolutionary events in East Asia remain unknown due to the underrepresentation of genomic diversity and the design of large-scale population studies. We reported one aggregated database of genome-wide-SNP variations from 796 Tai-Kadai (TK) genomes, including Bouyei first reported here, to explore the genetic history, population structure, and biological adaptative features of TK people from Southern China and Southeast Asia. We found geography-related population substructure among TK people using the state-of-the-art population genetic structure reconstruction techniques based on the allele frequency spectrum and haplotype-resolved phased fragments. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2024-04-23 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
|
|
Malaria resistance-related biological adaptation and complex evolutionary footprints inferred from one integrative Tai-Kadai-related genomic resource
|
Heliyon
|
10.1016/j.heliyon.2024.e29235
|
2024
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
Young Scientists Fund
|
82202078
|
Forensic exploratory study of high-resolution Y-SNP-STR co-typing in complex pedigree searches and paternal ancestry inference
|
|
|
| 提交者 |
Guanglin
He (Guanglinhescu@163.com)
|
| 提交单位 |
Institute of Rare Diseases, West China Hospital of Sichuan University |
| 提交日期 |
2023-12-22 |
