Accession |
PRJCA022313 |
Title |
Differentiated genomic footprints and connections inferred from 440 Hmong-Mien genomes suggest their isolation and long-distance migration |
Relevance |
Evolution |
Data types |
Targeted Locus (Loci)
|
Organisms |
Homo sapiens
|
Description |
The underrepresentation of Hmong-Mien (HM) people in Asian genomic studies has hindered our comprehensive understanding of the full landscape of their evolutionary history and complex trait architecture. South China is a multi-ethnic region and indigenously settled by ethnolinguistically diverse HM, Austroasiatic (AA), Tai-Kadai (TK), Austronesian (AN) and Sino-Tibetan (ST) people, which is regarded as East Asia's initial cradle of biodiversity. However, previous fragmented genetic studies have only presented a fraction of the landscape of genetic diversity in this region, especially the lack of haplotype-based genomic resources. The deep characterization of demographic history and natural-selection-relevant genetic architecture of HM people was necessary |
Sample scope |
Monoisolate |
Release date |
2024-02-02 |
Publication |
PubMed ID |
Article title |
Journal name |
DOI |
Year |
38273256
|
Differentiated genomic footprints suggest isolation and long-distance migration of Hmong-Mien populations
|
BMC Biology
|
10.1186/s12915-024-01828-x
|
2024
|
|
Grants |
Agency |
program |
Grant ID |
Grant title |
National Natural Science Foundation of China (NSFC)
|
Young Scientists Fund
|
82202078
|
Forensic exploratory study of high-resolution Y-SNP-STR co-typing in complex pedigree searches and paternal ancestry inference
|
|
Submitter |
Guanglin
He (Guanglinhescu@163.com)
|
Organization |
Institute of Rare Diseases, West China Hospital of Sichuan University |
Submission date |
2023-12-22 |