Accession |
PRJCA022612 |
Title |
Functional metagenomic and metabolomics analysis of gut dysbiosis induced by hyperoxia |
Relevance |
Medical |
Data types |
Metabolomics
|
Organisms |
Mus musculus
|
Description |
Inhaled oxygen is the first-line therapeutic approach for maintaining tissue oxygenation in critically ill patients, but usually exposes patients to damaging hyperoxia. Hyperoxia adversely increases the oxygen tension in the gut lumen which harbors the trillions of microorganisms playing an important role in host metabolism and immunity. Nevertheless, the effects of hyperoxia on gut microbiome and metabolome remain unclear, and metagenomic and metabolomics analysis were performed in this mouse study. |
Sample scope |
Monoisolate |
Release date |
2024-01-04 |
Publication |
|
Grants |
Agency |
program |
Grant ID |
Grant title |
National Natural Science Foundation of China (NSFC)
|
|
82160370
|
|
National Natural Science Foundation of China (NSFC)
|
|
82260167
|
|
|
Submitter |
Zhouxiong
Xing (xingzhouxiong111@126.com)
|
Organization |
Affiliated Hospitaol of Zunyi Medical Universtiy |
Submission date |
2024-01-04 |