Accession PRJCA022612
Title Functional metagenomic and metabolomics analysis of gut dysbiosis induced by hyperoxia
Relevance Medical
Data types Metabolomics
Organisms Mus musculus
Description Inhaled oxygen is the first-line therapeutic approach for maintaining tissue oxygenation in critically ill patients, but usually exposes patients to damaging hyperoxia. Hyperoxia adversely increases the oxygen tension in the gut lumen which harbors the trillions of microorganisms playing an important role in host metabolism and immunity. Nevertheless, the effects of hyperoxia on gut microbiome and metabolome remain unclear, and metagenomic and metabolomics analysis were performed in this mouse study.
Sample scope Monoisolate
Release date 2024-01-04
Publication
PubMed ID Article title Journal name DOI Year
10.3389/fmicb.2023.1197970
37840730 Functional metagenomic and metabolomics analysis of gut dysbiosis induced by hyperoxia Frontiers in Microbiology 10.3389/fmicb.2023.1197970 2023
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 82160370
National Natural Science Foundation of China (NSFC) 82260167
Submitter Zhouxiong Xing (xingzhouxiong111@126.com)
Organization Affiliated Hospitaol of Zunyi Medical Universtiy
Submission date 2024-01-04

Project Data

Resource name Description