| Accession |
PRJCA022740 |
| Title |
Multiomics study of heterogeneity in breast cancer |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Homo sapiens
|
| Description |
This study will systematically evaluate the intratumoral heterogeneity of breast cancer based on multi-omics research methods such as spatial transcriptomics, compare the differences in intratumoral heterogeneity of breast cancer with different pathological classifications, and analyze the relationship between intratumoral heterogeneity of breast cancer and the relationship between treatment resistance, recurrence, and metastasis of breast cancer, and the search for relevant molecular mechanisms and new therapeutic targets. |
| Sample scope |
Multiisolate |
| Release date |
2024-10-01 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 39023171
|
Inactivated cGAS-STING Signaling Facilitates Endocrine Resistance by Forming a Positive Feedback Loop with AKT Kinase in ER+HER2- Breast Cancer
|
Advanced Science
|
10.1002/advs.202403592
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
82172722
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82173092
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82373378
|
|
|
|
| Submitter |
Zeyu
Li (lizeyu@genomics.cn)
|
| Organization |
BGI research |
| Submission date |
2024-01-09 |
