Accession PRJCA023129
Title The treatment effects of human endometrial stem stromal cells in intrauterine adhesion of human,rat, and non-human primates
Relevance Medical
Data types Transcriptome or Gene expression
Organisms Rattus
Homo sapiens
Description 1.Location, isolation, purification, culture, expansion, and identification of human endometrial stem / stromal cells.2.Establishment of animal models of intrauterine adhesion.3.To develop new tissue-engineered biomaterials that can load human endometrial stem / stromal cells for treating animal models of intrauterine adhesion (IUA) and to explore strategies to prevent and reverse IUA.4.High throughput single-cell sequencing (10x genomics) of human endometrium (patients with normal uterus and intrauterine adhesion) to explore key genes and regulatory mechanisms for reversing IUA.
Sample scope Monoisolate
Release date 2024-01-24
Publication
PubMed ID Article title Journal name DOI Year
38902788 Restoration of functional endometrium in an intrauterine adhesion rat model with endometrial stromal cells transplantation Stem Cell Research & Therapy 10.1186/s13287-024-03788-z 2024
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) Key Program 32130034
National Natural Science Foundation of China (NSFC) Major Program 82192874
Ministry of Science and Technology of the People's Republic of China (MOST) National Key Technologies R&D Program 2022YFA1103100
Ministry of Science and Technology of the People's Republic of China (MOST) National Key Technologies R&D Program 2021YFA0805700
Natural Science Foundation of Yunnan Province 202102AA100053
Natural Science Foundation of Yunnan Province YNWR-YLXZ-2020-015
Spring City Plan. Science and Technology Programs Youth Project of Yunnan Provincial Department of Science and Technology 202201AU070232
Submitter tianqing Li (litq@lpbr.cn)
Organization Institute of Primate Translational Medicine, Kunming University of Science and Technology
Submission date 2024-01-24

Project Data

Resource name Description