| 描述信息 |
Infertility, a worldwide reproductive health concern, impacts approximately one in five couples. Male infertility, stemming from spermatogenic dysfunction and reduced sperm quality, stands as a primary factor contributing to infertility. Given the global decrease in male fertility linked to environmental factors like the greenhouse effect, it is crucial to develop a comprehensive understanding of how increased temperatures impact both the quantity and quality of sperm. In this study, we investigated the expression profile of small non-coding RNAs (sncRNAs) in the testicular tissue of mice subjected to heat stress.The investigation explores the dynamic shifts in small non-coding RNAs (sncRNAs) within the mouse testis under heat stress, revealing insights into changes in miRNAs, tsRNAs, piRNAs, rsRNAs, and other sncRNAs. Furthermore, we successfully identified differentially expressed sncRNAs in testicular tissues before and after heat stress. Subsequently, we conducted functional enrichment analysis on the potential predicted target genes of differentially expressed miRNAs and tsRNAs.These datasets will serve as a valuable data foundation for further research on the decline in male reproductive capacity induced by heat stress. |
