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项目编号 PRJCA023492
项目标题 DVT metabolome
涉及领域 Medical
数据类型 Phenotype or Genotype
物种名称 Homo sapiens
描述信息 Deep vein thrombosis (DVT) is a leading cause of morbidity and mortality after trauma. The occurrence of DVT after trauma (pt-DVT) undergoes profound metabolic changes, but a comprehensive characterization in humans is lacking. Here, we performed metabolomics analysis to evaluate the metabolic alterations and their function in patients with and without DVT after trauma. Our study comprehensively delineates the metabolic and hematological dysregulations for pt-DVT.
样品范围 Multiisolate
发布日期 2024-07-25
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
39244606 Integrated landscape of plasma metabolism and proteome of patients with post-traumatic deep vein thrombosis Nature Communications 10.1038/s41467-024-52262-0 2024
Plasma Metabolomics and Machine Learning Reveals Metabolic Alterations and Diagnostic Biomarkers for Deep Venous Thrombosis in Hypertensive Patients after Traumatic Fracture Journal of Proteome Research 10.1021/acs.jproteome.5c00094 2025
41902882 Multi-omics analyses reveal novel metabolic signatures of post-traumatic deep vein thrombosis in patients with coronary heart disease Metabolomics 10.1007/s11306-026-02419-3 2026
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
National Natural Science Foundation of China (NSFC) 32170616
National Natural Science Foundation of China (NSFC) 32170616
National Natural Science Foundation of China (NSFC) 32170616
Key Research and Development Project of Shaanxi Province 2019ZDLSF01-09
Key Research and Development Project of Shaanxi Province 2022SF-394
Key Research and Development Project of Shaanxi Province 2022GXLH-01-22
Science Fund for Distinguished Young Scholars of Shaanxi Province 2021JC-02
Innovation Capability Support Program of Shaanxi Province 2022TD-44
Science and Technology Planning Project of Xi 2019115713YX012SF052
Fundamental Research Funds for the Central Universities NA
提交者 Tie-Lin Yang (yangtielin@xjtu.edu.cn)
提交单位 Xi'an Jiaotong University
提交日期 2024-02-06

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